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You can do anything!

I remember listening to a headteacher in an assembly once saying to the children to take every opportunity they possible can as the grow up, since these opportunities are like doors and as you get older they close. I know I am never going to be a gymnast now or even a concert pianist (sorry mum) but is it possible to actually learn how to do something, or do you need to have some sort of natural talent in the subject first.